| Autor: |
Duru, O. Kenrik, Mangione, Carol M., Turk, Norman, Chon, Janet, Fu, Jeffery, Cheng, Grace, Cheng, Felicia, Moss, Amanda, Frosch, Dominick, Jeffers, Kia Skrine, Castellon-Lopez, Yelba, Tseng, Chi-Hong, Maranon, Richard, Norris, Keith C., Moin, Tannaz |
| Předmět: |
|
| Zdroj: |
Diabetes Care; Dec2023, Vol. 46 Issue 12, p2218-2222, 5p |
| Abstrakt: |
OBJECTIVE: We conducted a cluster-randomized, shared decision-making (SDM) trial offering lifestyle change, metformin, or both options, to adults at risk for diabetes in a primary care network (n = 20 practices). RESEARCH DESIGN AND METHODS: We used propensity score matching to identify control patients and used electronic health record data to compare weight loss at 24 and 36 months of follow-up and diabetes incidence at 36 months of follow-up. RESULTS: In adjusted post hoc analyses, SDM participants (n = 489) maintained modestly greater 24-month weight loss of −3.1 lb and 36-month weight loss of −2.7 lb versus controls (n = 1,430, both comparisons P < 0.001). SDM participants who chose both lifestyle change and metformin sustained weight loss at 36 months of −4.1 lb (P < 0.001 vs. controls). We found no differences in incident diabetes (15% of SDM participants, 14% of control participants; P = 0.64). CONCLUSIONS: This is one of the first studies to demonstrate weight loss maintenance up to 36 months after diabetes prevention SDM. [ABSTRACT FROM AUTHOR] |
| Databáze: |
Complementary Index |
| Externí odkaz: |
|
