Autor: |
Biswas, Subhamoy, Shit, Sudip, Behera, Bipin Kumar, Sahu, Archana Kumari, Saikia, Anil K. |
Předmět: |
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Zdroj: |
Chemical Communications; 12/14/2023, Vol. 59 Issue 96, p14301-14304, 4p |
Abstrakt: |
A TfOH-promoted, metal-free protocol has been unveiled for the synthesis of spiro-furan quinazolinones employing alkynol urea derivatives utilizing alkynyl Prins cyclization reaction. This methodology produces highly functionalized spiro-heterocycles in excellent yields with exclusive E-selectivity under ambient conditions. Furthermore, late-stage modifications incorporate bromide and acetyl functionalities into the synthesized spiro-heterocycles. [ABSTRACT FROM AUTHOR] |
Databáze: |
Complementary Index |
Externí odkaz: |
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