| Abstrakt: |
Breast cancer is considered to be the third most common cancer worldwide. Most patients undergo breast reconstruction as the primary intervention post-resection, either as implant-based, autologous reconstruction, or both. We aim to review the common risk factors and complications following implant-based reconstruction (IBR) surgeries. This systematic review was designed and conducted using PRISMA guidelines. The literature was systematically searched in November 2021 using the following databases: MEDLINE, Cochrane, and EMBASE. Among the terms used to aid the search were the following: breast reconstruction, IBR, breast-implant or implant, and post-operative complications. Reviewing the literature resulted in a total of 329 publications. After implementing our criteria, 23 articles were included in this study, with a total of 15,751 patients, of whom 8661 patients underwent IBR and 7090 underwent delayed surgeries. Our meta-analysis resulted in higher risks of wound dehiscence (RR = 1.59), skin necrosis (RR = 1.9), and reoperation (RR = 1.3) following IBR. Analysis of pooled data revealed a significantly higher risk of skin necrosis, wound dehiscence, implant deflation/rupture, and reoperation rate in immediate implant-based reconstruction in comparison to delayed implant-based reconstruction. Furthermore, the overall complication rate was not significantly different between the two groups. Level of evidence: Not gradable [ABSTRACT FROM AUTHOR] |
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