| Abstrakt: |
A recent study conducted in Zaragoza, Spain, explored the role of the intestine, kidney, and various hormones in adapting to changes in dietary phosphate concentration in rats. The researchers found that both the jejunum and kidney cortex exhibited regulated phosphate transport after chronic feeding of different phosphate diets in normal rats. However, acute dietary adaptations were only observed in the kidney cortex. The study also revealed that certain hormones, such as PTH and FGF23, were regulated by all diet changes, even in fasting animals. These findings provide new insights into phosphate adaptations and highlight the lack of correlation between phosphate transport, NaPi2a expression, and PTH/FGF23 concentrations. [Extracted from the article] |
