Findings from Korea University Has Provided New Data on Tissue Engineering (Tumor-specific Release of Copper-incorporated Diethyldithiocarbamate From an Optimized Apoferritin Scaffold Enables Both Potent and Safe Anti-cancer Therapy).

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Zdroj: Drug Week; 12/8/2023, p328-328, 1p
Abstrakt: Researchers at Korea University in Seoul, South Korea have developed a new approach to cancer therapy that addresses the challenges of off-target toxicity and multidrug resistance. They used an optimized scaffold-conjugated drug called copper ion-incorporated diethyldithiocarbamate (Cu-DDC2) to deliver targeted treatment to tumor cells while minimizing harm to normal tissues. In experiments with xenograft mice, the Cu-DDC2 treatment effectively suppressed the growth of pancreatic and gastric cancer without causing pathological abnormalities in healthy cells. This innovative approach shows promise for safe and potent cancer therapy. [Extracted from the article]
Databáze: Complementary Index