| Předmět: |
|
| Zdroj: |
Genomics & Genetics Weekly; 12/8/2023, p1274-1274, 1p |
| Abstrakt: |
A recent report from Kyoto University in Japan discusses the role of ErbB-family receptors in the proliferation, migration, and survival of epithelial cells. The researchers conducted experiments to determine the contribution of each ErbB gene and found that ERK1/2 activation waves during cell migration were primarily mediated by ErbB1 and secondarily by the ErbB2 and ErbB3 heterodimer. They also discovered that a ligand-independent ErbB2 activity is sufficient for preventing apoptosis at high cell density. This research provides valuable insights into the roles of each ErbB receptor. [Extracted from the article] |
| Databáze: |
Complementary Index |
| Externí odkaz: |
|
