| Abstrakt: |
To investigate the relationship between splenic vein diameter (SVD), portal vein diameter (PVD), and semi-quantitative scoring and liver fibrosis in patients with hepatitis B. A total of 202 patients with hepatitis B who underwent ultrasound-guided liver biops. Based on the results of liver biopsy, the patients were divided into the liver fibrosis group (n = 112) and the non-fibrosis group (n = 90). Logistic regression analysis was used to explore the relationship between various indicators and liver fibrosis in patients with hepatitis B. A predictive model for liver fibrosis and a risk scoring system were constructed, and risk levels were determined. The results showed that Elevated SVD, elevated PVD, increased splenic thickness, increased spleen area, increased gallbladder wall thickness, increased liver surface membrane height, increased peak blood flow velocity of the hepatic artery (HAVmx), increased liver stiffness measurement (LSM), and elevated alanine aminotransferase (ALT) were independent risk factors for liver fibrosis in patients with hepatitis B. Decreased spleen length, decreased liver parenchymal echo, decreased clarity of liver veins, increased peak blood flow velocity of the portal vein (PVVmax), and increased peak blood flow velocity of the splenic vein (SVVmax) were protective factors (P<0.05). SVD and PVD had a significant nonlinear relationship with liver fibrosis in hepatitis B patients (P<0.05). Risk scoring was performed for each influencing factor, with a total score ranging from 0.5 to 24. Based on the percentiles, the scores were classified into low-risk group (n = 84) with a score <9, moderate-risk group (n = 67) with a score of 9~17, and high-risk group (n=51) with a score >17. The incidence of liver fibrosis in the high-risk group was significantly higher than that in the low-risk and moderate-risk groups (P<0.05). SVD and PVD are significantly higher in patients with hepatitis B-related fibrosis compared to those without fibrosis and are closely related to the degree of liver fibrosis. [ABSTRACT FROM AUTHOR] |
