| Abstrakt: |
Introduction: Autoimmune hepatitis is a rare form of liver inflammation, it can present as acute hepatitis to chronic liver disease and cirrhosis. It is divided into two types autoimmune hepatitis-1 and autoimmune hepatitis-2 based on the involved antibodies. Corticosteroids are effective and life-saving therapeutic agents. Case Report: This is a case report of a 61-year-old female nonalcoholic with a known case of vitiligo. She presented to us with a complaint of fever for the last two months and yellowish discoloration of eyes for the last one month and pain abdomen for the last 10 days. On initial work-up Haemoglobin was 10.9, mild thrombocytopenia 131000, Liver enzymes (SGOT/SGPT - 350/650), Total bilirubin/Direct-22/16, total protein/albumin-5.9/2.9, alkaline phosphatase-124, coagulation profile (PT/INR-38/3.5). On further evaluation viral markers were negative, autoimmune marker (ANA-negative, ASMA-negative, Anti LKM-negative, AMA-negative, ALC-1 [Antiliver cytosol] was positive). Other etiological screening was negative. A liver biopsy was suggestive of interface hepatitis. The diagnosis was made type-2 autoimmune hepatitis. The patient was started on steroids and azathioprine. After 6 months of follow-up, the patient is symptomatically better with normalization of the liver function test. Conclusion: Autoimmune hepatitis without treatment has a poor prognosis, so it becomes important to maintain a high index of suspicion for the disease in older persons people too. A prompt diagnosis is important for a better prognosis. [ABSTRACT FROM AUTHOR] |
