| Abstrakt: |
A recent study conducted at University Hospital Ramon & Cajal in Madrid, Spain, focused on identifying the variables associated with the development of non-criteria manifestations in the presence of antiphospholipid antibodies (aPLs) in a pediatric cohort. The study included 82 children, with 8.5% experiencing thrombotic events (TEs) and 69.5% experiencing non-criteria manifestations. Haematological manifestations were the most frequent, followed by cutaneous, neurological, and cardiac events. The study found that a positive family history of autoimmune diseases and the absence of TEs were independent risk factors for developing non-criteria manifestations. The researchers suggest that including these manifestations as classification criteria for antiphospholipid syndrome (APS) in the pediatric population could lead to improved prognosis. [Extracted from the article] |
