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| Zdroj: |
Genomics & Genetics Weekly; 12/01/2023, p687-687, 1p |
| Abstrakt: |
Researchers at the Institute of Cytology and Genetics in Novosibirsk, Russia, have conducted a study on Alzheimer's disease (AD) using OXYS rats as a model. They investigated the maturation of the blood-brain barrier (BBB) in the hippocampus and frontal cortex of these rats during the first three weeks of life. The study found altered expression of BBB-associated genes and a delay in vascularization and pericyte coating of blood vessels in the OXYS rats. These findings suggest that early-life vascular dysfunction may contribute to the development of AD later in life. [Extracted from the article] |
| Databáze: |
Complementary Index |
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