| Abstrakt: |
A study conducted by researchers at NOVA Southeastern University in Davie, Florida, has investigated the effects of interleukin-34 (IL-34) on alveolar bone loss in a ligature-induced model of periodontitis. The study found that IL-34 promotes alveolar bone loss in periodontal lesions, while anti-IL-34 neutralizing monoclonal antibody reduces bone loss and the number of osteoclasts in these lesions. The research suggests that anti-IL-34 monoclonal antibody-based therapeutic regimens may be effective in suppressing alveolar bone loss in periodontitis lesions. This study provides new insights into the role of IL-34 in periodontal bone loss and offers potential avenues for treatment. [Extracted from the article] |
