| Abstrakt: |
A recent study conducted in Galway, Ireland, examined the reproductive toxicity of hexachlorocyclohexane (HCH) in men. HCH is a widely distributed organochlorine pesticide and endocrine modulator. The study found that men exposed to HCH had higher levels of HCH and malondialdehyde (MDA) in their blood, indicating oxidative stress. Additionally, the exposed group had lower levels of the antioxidant glutathione (GSH) and poorer semen quality, leading to a higher prevalence of infertility. The study also identified genetic alterations in the SRY and AZF genes, as well as microdeletions and point mutations, which may contribute to male infertility. [Extracted from the article] |
