| Abstrakt: |
A study conducted by researchers at the University of Madras in Chennai, India, has developed new cobalt, copper, and zinc complexes of Schiff-base ligands as potential chemotherapeutic agents. The ligands were synthesized and characterized using various spectroscopic and analytical techniques. The complexes showed high binding affinity to CT-DNA and exhibited antioxidant properties. In cell viability studies, the copper complexes demonstrated better efficacy against a human breast adenocarcinoma cell line compared to a human cervical carcinoma cell line. The research concluded that the copper complexes using ligand L2 were particularly effective and could be considered as potent DNA-targeting drugs. [Extracted from the article] |
