Abstrakt: |
A recent study conducted by researchers at the University of Catania in Italy provides new insights into adverse drug reactions (ADRs). ADRs are defined as noxious and unintended responses to medication, excluding poisoning, accidental, or intentional overdoses. The occurrence of ADRs varies depending on the approach used to define and detect them, as well as the characteristics of the population being studied. ADRs have a significant impact on morbidity and mortality, particularly among older adults, and can be a financial burden for healthcare services. Between 30% and 60% of ADRs may be predictable and preventable, resulting from inappropriate prescription, drug toxicity, age- and sex-related anomalies in drug absorption and metabolism, and drug-drug interactions. The study suggests that interventions focused on pharmaceutical principles, such as medication review and reconciliation, should be integrated into a broader assessment of patients' characteristics and needs. Digital health interventions could also assist healthcare professionals in identifying inappropriate prescriptions and promoting patient adherence to pharmacotherapies. [Extracted from the article] |