| Abstrakt: |
Objective To analyze the data on the disease burden of ALD in China from 1990 to 2019, so as to provide a reference for the prevention and control of ALD. Methods The data on the morbidity, mortality, and DALY rate of ALD in China from 1990 to 2019 were collected from the GBD 2019 to describe the disease burden, Joinpoint regression model was used to analyze the time trend of ALD morbidity and mortality, and APC model was used to investigate the effects of age, period and cohort on ALD morbidity and mortality. Results From 1990 to 2019, the standardized morbidity of ALD in China showed an upward trend ( AAPC = 0. 12% ), and the standardized mortality and DALY rate showed a downward trend ( AAPC = -2. 43%, AAPC = -2. 65% ). The morbidity, mortality, and DALY rates of males were higher than those of females. The results of the age effect showed that the risk of ALD in males was the highest at the age of 45 -49, with an RR of 8. 01. The risk of disease in females was the highest at the age of 50 - 54, with an RR of 12. 07. The risk of death increases with age. The period effect results showed that the incidence risk and mortality risk of ALD was gradually reduced, the birth cohort effect showed that the incidence risk of ALD generally increased with the birth cohort, and the mortality risk generally decreased with the birth cohort. Conclusion As a whole the morbidity of ALD in China is on the rise, and the mortality and DALY rate are on the decline. There are gender and age differences in the risk of morbidity and mortality. [ABSTRACT FROM AUTHOR] |
