Evaluation of Pathological Responses and Breast MRI Images in Breast Cancer Patients Who Have Received Neoadjuvant Therapy: A Single Center Experience.

Autor: Dağıstanlı, Sevinç, Sönmez, Süleyman, Gündüz, Nermin, Bulut, Nilüfer
Předmět:
Zdroj: Comprehensive Medicine; Oct2023, Vol. 15 Issue 4, p361-367, 7p
Abstrakt: Objective: In the present study, pre-operative magnetic resonance imaging (MRI) responses following neoadjuvant chemotherapy (NAC) administration were compared with postoperative pathological response rates. The study design was retrospective cross sectional method. Materials and Methods: Breast MRI is helpful in determining treatment plans, responses, and prospective survival analyses in breast cancer patients receiving neoadjuvant chemotherapy. A total of 39 patients receiving NAC between January 2019 and June 2020 were analyzed in the hospital. Treatment responses after NAC in patients with locally advanced who had not received any treatment before were evaluated with MRI. The longest diameter was recorded as well as the transfers of the primary tumor and axillary lymph node. The correlation of response rates obtained with the MRI with pathological specimen results was also examined. Results: When the pathological clinical response (pCR) was compared with the radiological response of the tumor and lymph node, the sensitivity was found to be 52.6% and 70.5%, and the accuracy was 64.1% and 51.2%, respectively. Conclusion: The preferred MRI techniques and sequence intervals, and the histopathological characteristics of the tumor increase the accuracy rates in reaching pathological complete response rates. [ABSTRACT FROM AUTHOR]
Databáze: Complementary Index