| Autor: |
Ulgen Tekerek, Nazan, Dursun, Oguz, Asilioglu Yener, Nazik, Yildizdas, Dincer, Anıl, Ayşe Berna, Kendirli, Tanil, Koker, Alper, Karalok, Selen, Aksoy, Ayşe, Kinik Kaya, Elif, Ekinci, Faruk, Incecik, Faruk, Olgac Dundar, Nihal, Durak, Fatih, Botan, Edin, Havan, Merve, Sahin, Suleyman, Duman, Ozgur, Haspolat, Senay |
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| Zdroj: |
Child's Nervous System; Nov2023, Vol. 39 Issue 11, p3207-3214, 8p |
| Abstrakt: |
Purpose: The aim of this study was to determine the clinical, laboratory, and radiological factors related with posttraumatic epilepsy (PTE). Methods: The study is a multicenter descriptive cross-sectional cohort study. Children who followed up for TBI in the pediatric intensive care unit between 2014 and 2021 were included. Demographic data and clinical and radiological parameters were recorded from electronic case forms. All patients who were in the 6-month posttraumatic period were evaluated by a neurologist for PTE. Results: Four hundred seventy-seven patients were included. The median age at the time of trauma was 66 (IQR 27–122) months, and 298 (62.5%) were male. Two hundred eighty (58.7%) patients had multiple traumas. The mortality rate was 11.7%. The mean duration of hospitalization, pediatric intensive care unit hospitalization and mechanical ventilation, Rotterdam score, PRISM III score, and GCS at admission were higher in patients with epilepsy (p < 0.05). The rate of epilepsy was higher in patients with severe TBI, cerebral edema on tomography and clinical findings of increased intracranial pressure, blood transfusion in the intensive care unit, multiple intracranial hemorrhages, and intubated patients (p < 0.05). In logistic regression analysis, the presence of intracranial hemorrhage in more than one compartment of the brain (OR 6.13, 95%CI 3.05–12.33) and the presence of seizures (OR 9.75, 95%CI 4.80–19.83) were independently significant in terms of the development of epilepsy (p < 0.001). Conclusions: In this multicenter cross-sectional study, intracranial hemorrhages in more than one compartment and clinical seizures during intensive care unit admission were found to be independent risk factors for PTE development in pediatric intensive care unit patients with TBI. [ABSTRACT FROM AUTHOR] |
| Databáze: |
Complementary Index |
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