| Autor: |
TORU AOYAMA, ITARU HASHIMOTO, YUKIO MAEZAWA, KENTARO HARA, KEISUKE KAZAMA, MASAKATSU NUMATA, NATSUMI KAMIYA, HIROSHI TAMAGAWA, SHO SAWAZAKI, SHINNOSUKE KAWAHARA, KEISUKE KOMORI, AYAKO TAMAGAWA, HARUHIKO CHO, JUNYA MORITA, KAZUKI OTANI, AYA KATO, MIE TANABE, TAKASHI OSHIMA, NORIO YUKAWA, AYA SAITO |
| Předmět: |
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| Zdroj: |
In Vivo; Nov/Dec2023, Vol. 37 Issue 6, p2696-2703, 8p |
| Abstrakt: |
Background/Aim: The platelet-to-lymphocyte ratio (PLR) is a promising prognostic marker in some malignancies. The present study evaluated the clinical impact of the PLR in patients with gastric cancer who underwent curative resection. Patients and Methods: This study included 258 patients who underwent curative treatment for gastric cancer between 2005 and 2020. The prognosis and clinicopathological parameters between the high- and low- PLR statuses were analyzed. Results: The overall survival (OS) stratified by each clinical factor was compared using the log-rank test, and a significant difference was observed using a pretreatment PLR of 150. When comparing the patient backgrounds between the high-PLR (PLR≥150) and low-PLR (PLR<150) groups, there were no significant differences between the two groups. The OS rates at 3 and 5 years after surgery were significantly higher at 70.8% and 60.4%, respectively, for the high-PLR group than at 83.6% and 79.7%, respectively, for the low-PLR group. Univariate and multivariate analyses of the OS showed that the PLR was a significant prognostic factor. In addition, when comparing the first recurrence sites, there were significant differences in peritoneal recurrence. Conclusion: The PLR is a significant risk factor for gastric cancer, making it a promising prognostic factor for patients with gastric cancer. [ABSTRACT FROM AUTHOR] |
| Databáze: |
Complementary Index |
| Externí odkaz: |
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