Research on Cancer Detailed by Researchers at Affiliated Changzhou No. 2 People's Hospital of Nanjing Medical University (Thymidine kinase 1 as a target is regulated by the hsa-let-7b-5p/LINC00665 axis and affects NSCLC prognosis).

Předmět:	RESEARCH personnel THYMIDINE NON-small-cell lung carcinoma CANCER research PROGNOSIS
Zdroj:	Cancer Gene Therapy Week; 11/16/2023, p31-31, 1p
Abstrakt:	Researchers at Affiliated Changzhou No. 2 People's Hospital of Nanjing Medical University in China have conducted a study on the impact of thymidine kinase 1 (TK1)-related competitive endogenous RNA (ceRNA) networks on the prognosis of non-small cell lung cancer (NSCLC). The study found that NSCLC tissues expressed significantly higher levels of TK1 compared to normal tissues, and patients with high TK1 expression had a worse prognosis. The study also identified a ceRNA network involving LINC00665/has-let-7b-5p/TK1 that could influence the growth and prognosis of NSCLC. The researchers suggest that TK1 could be a prognostic biomarker and a potential therapeutic target for predicting NSCLC prognosis. [Extracted from the article]
Databáze:	Complementary Index
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