Abstrakt: |
A recent study conducted by researchers at the University of Liege in Belgium explored the effects of dexmedetomidine sedation on cortical excitability in the brain. The study involved 20 healthy subjects and measured transcranial magnetic stimulation (TMS) and EEG activity in the frontal and parietal cortex. The results showed that the amplitude of TMS-evoked potential (TEP) increased in the frontal cortex during sedation, but not in the parietal cortex. Additionally, the study found that the depth of sedation had a non-linear effect on TEP amplitude, with a paradoxical increase in certain regions. The researchers suggest that further investigation is needed to understand the relationship between cortical excitability and sedation depth. [Extracted from the article] |