Studies from Ordu University Education and Research Hospital Describe New Findings in Klebsiella pneumoniae (Evaluating molecular epidemiology of carbapenem non-susceptible Klebsiella pneumoniae isolates with MLST, MALDI-TOF MS, PFGE).

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Zdroj: Genomics & Genetics Weekly; 11/17/2023, p1804-1804, 1p
Abstrakt: A study conducted at Ordu University Education and Research Hospital in Turkey aimed to evaluate the antibiotic resistance and virulence genes, as well as the clonal relationship, of carbapenem non-susceptible Klebsiella pneumoniae strains. The researchers used molecular methods such as PCR, immunochromatographic tests, PFGE, MLST, and MALDI-TOF MS to analyze the strains. The study found that the most common resistance genes were bla SHV, bla CTX-M-1, bla OXA-48, bla KPC, bla TEM, and bla NDM, while the most common virulence genes were magA, kpn, and K2. The researchers also observed differences between bacterial identifications made with VITEK-2 and MALDI-TOF MS. This study provides valuable insights into the molecular epidemiology of carbapenem non-susceptible Klebsiella pneumoniae isolates. [Extracted from the article]
Databáze: Complementary Index