New Bacteriophages Research Has Been Reported by Researchers at Stanford University (Bacterial outer membrane vesicles bound to bacteriophages modulate neutrophil responses to bacterial infection).

Předmět:	EXTRACELLULAR vesicles BACTERIAL cell walls BACTERIAL diseases RESEARCH personnel BACTERIOPHAGES RHAMNOLIPIDS
Zdroj:	Genomics & Genetics Weekly; 11/17/2023, p878-878, 1p
Abstrakt:	A recent study conducted by researchers at Stanford University explores the impact of bacteriophages on mammalian immunity. The study focuses on the bacteriophage Pf4, which is produced by the pathogen Pseudomonas aeruginosa. The researchers found that Pf4 phages dampen inflammatory responses to bacterial endotoxin by binding to bacterial outer membrane vesicles (OMVs). These OMVs contain short RNAs that trigger the production of interferons and inhibit the production of antibacterial cytokines and chemokines. The study suggests that bacteriophages may alter innate immunity to bacterial infection, potentially reducing inflammation at sites of colonization or infection. [Extracted from the article]
Databáze:	Complementary Index
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