| Autor: |
Fearon, Ian M., Seltzer, Ryan G. N., Houser, Trisha L., Tope, Andrew, Cahours, Xavier, Verron, Thomas, Malt, Layla, Nahde, Thomas, O'Connell, Grant, Nides, Mitchell |
| Zdroj: |
Drug Testing & Analysis; Oct2023, Vol. 15 Issue 10, p1270-1280, 11p |
| Abstrakt: |
Background: Greater nicotine delivery is associated with higher nicotine concentrations in electronic nicotine delivery system (ENDS) liquids. However, there is a current debate as to whether this leads to increased dependence and mitigates ENDS public health potential. Methods: Self‐reported dependence among users of myblu ENDS containing different nicotine concentrations was examined with data from a multiwave cross‐sectional survey of US young adults and adults. Questions examined responses related to dependence measures and participants' most often used myblu ENDS nicotine concentration (low: 0%, 1% and 1.2%; medium: 2%, 2.4% and 2.5%; or high: 3.6% and 4%). Results: A global general linear model using nicotine concentration, age and days myblu that was used in the past 30 revealed a significant difference in PROMIS scores among nicotine concentration groups (F = 4.07, p = 0.02). However, pairwise comparisons to examine which specific groups differed significantly from others showed no significant differences. Logistic regression demonstrated that strong past 30‐day cravings to use myblu among participants using high or medium nicotine concentrations were not significantly different from those using a low concentration (ORs 0.66 [0.42, 1.03], p = 0.07 and 0.95 [0.49, 1.82], p = 0.98, respectively). Time to daily first use for high or medium nicotine concentration users was not significantly different from those using a low concentration (ORs 0.89 [0.70, 1.14], p = 0.35 and 0.84 [0.57, 1.25], p = 0.40, respectively). Conclusions: Use of myblu ENDS with different nicotine concentrations is not associated with differing levels of dependence. Our findings contradict the notion that high ENDS e‐liquid nicotine levels generate increased dependence. [ABSTRACT FROM AUTHOR] |
| Databáze: |
Complementary Index |
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