| Autor: |
Wani, Aabid A., Mehta, Kriti, Reddy, Rajeswara, Bharatam, Prasad V. |
| Předmět: |
|
| Zdroj: |
New Journal of Chemistry; 11/21/2023, Vol. 47 Issue 43, p19983-19986, 4p |
| Abstrakt: |
Carbon–carbon bond forming processes are central to synthetic organic chemistry, and the Michael addition reaction is a frequently used method for C–C bond formation; many organocatalysts have been utilised to facilitate this reaction. In this article, 1,1-diaminoazine-catalysed Michael addition reaction of malonates (nucleophiles) with nitro-olefins (electrophiles) is reported. The bifunctional character of the organocatalyst facilitates the C–C bond formation. The catalytic site comprises a guanidine portion and an imine group, which helps in hydrogen bond exchange. This catalytic process affords Michael adducts with good to moderate yields over a wide range of substrates. The control experiments support the bifunctional nature of the catalyst. [ABSTRACT FROM AUTHOR] |
| Databáze: |
Complementary Index |
| Externí odkaz: |
|
