Atropinium dithiophosphates and dithiophosphonates on the basis of α-D-glucofuranose and α-D-galactopyranose diacetonide scaffolds.

Autor: Nizamov, Ilyas S, Shumatbaev, Georgiy G, Nizamov, Ilnar D, Urazbakhtin, Varis R, Shulaeva, Marina P, Pozdeev, Oscar K, Batyeva, Elvira S
Zdroj: Journal of Chemical Sciences; Dec2023, Vol. 135 Issue 4, p1-6, 6p
Abstrakt: Optically active dithiophosphoric and dithiophosphonic acids bearing glucofuranose and galactopyranose diacetonide substituents reacted with racemic atropine to give atropinium dithiophosphates or dithiophosphonates as the mixture of diastereomers. Dithiophosphoric and dithiophosphonic acids and their atropinium salts possess antimicrobial activity. SYNOPSIS: Optically active dithiophosphoric and dithiophosphonic acids bearing α-D-glucofuranose and α-D-galactopyranose diacetonide substituents reacted with racemic atropine to give atropinium dithiophosphates or dithiophosphonates as the mixture of diastereomers. Dithiophosphoric and dithiophosphonic acids and their atropinium salts possess antimicrobial activity. [ABSTRACT FROM AUTHOR]
Databáze: Complementary Index
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