Monozygotic twins and cholesteatomas: nature or nuture?

Autor: Brar, Sabrina, Wolf, Dennis M., Faoury, Morad, Barwell, Julian, Saggar, Anand, Daya, Hamid
Předmět:
Zdroj: European Archives of Oto-Rhino-Laryngology; Dec2023, Vol. 280 Issue 12, p5649-5654, 6p
Abstrakt: Purpose: Cholesteatoma is a rare middle ear pathology. It can be classified into acquired and congenital forms. Although benign, cholesteatomas can cause significant morbidity including hearing loss, infection, facial palsy and thrombosis. Congenital cholesteatomas are incredibly rare and bilateral disease has not commonly been published in the literature. Method: We describe the case of female identical (monozygotic, monochorionic, diamniotic) twins who both developed congenital cholesteatomas. In this report, we review the aetiology, treatment, embryology and pathology of cholesteatoma. Results: The patients have been followed up 15 years after their initial surgery with promising results - pure-tone audiometry and repeat scans have not illustrated any disease recurrence. Conclusion: This paper presents one of the only cases of female monozygotic twins presenting with unilateral and bilateral cholesteatomas. [ABSTRACT FROM AUTHOR]
Databáze: Complementary Index