| Autor: |
Lajdam, Ghassan Bin, Alahmadi, Rana A., Alhakami, Mohammed, Ghaddaf, Abdullah A., Abdulhamid, Ahmed S., Alahmadi, Asma, Abdelsamad, Yassin, Hagr, Abdulrahman |
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| Zdroj: |
European Archives of Oto-Rhino-Laryngology; Dec2023, Vol. 280 Issue 12, p5153-5165, 13p |
| Abstrakt: |
Purpose: To compare the efficacy and safety of temporalis fascia (TF) with cartilage grafts for primary type 1 tympanoplasty in chronic otitis media (COM) patients. Methods: Computerized search was performed in MEDLINE, Embase, and CENTRAL. Eligible for inclusion were randomized controlled trials (RCTs) comparing TF and cartilage grafts in individuals with non-cholesteatoma COM and intact ossicles requiring type 1 tympanoplasty. Primary outcomes were graft success and hearing improvement, measured by the air–bone gap (ABG) closure. The secondary outcome was the occurrence of complications. Standardized mean differences (SMD) and odds ratios (OR) with 95% confidence intervals were calculated. Results: Eighteen RCTs that enrolled 1273 participants were found eligible. Data were reported at follow-up periods ranging from 6 weeks to 24 months. The pooled effect estimate revealed a higher and statistically significant graft success favoring cartilage grafts at 12 months (OR = 2.24, 95% CI 1.33–3.78) and 24 months (OR = 2.96, 95% CI 1.18–7.43). There was no significant difference between both grafts in post-operative ABG closure across all follow-up periods (6 weeks to 12 months). Conclusions: Compared to TF, primary type 1 cartilage tympanoplasty offers better graft uptake rates and comparable postoperative hearing outcomes for COM patients. [ABSTRACT FROM AUTHOR] |
| Databáze: |
Complementary Index |
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