| Autor: |
Neilan, Barbara A., Taddeini, L., McJilton, C. E., Handwerger, B. S. |
| Předmět: |
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| Zdroj: |
Clinical & Experimental Immunology; Jan1980, Vol. 39 Issue 1, p746-749, 4p |
| Abstrakt: |
The immune responsiveness of mice given low levels of lead acetate (1300 p.p.m.) in their drinking water for 8 weeks was determined. Mean percentages of splenic T and B lymphocytes in lead-exposed mice were slightly lower than in controls. Mean mitogen response to phytohaemagglutinin and concanavalin A in mice exposed to lead was significantly decreased compared to controls. The response to lipopolysaccharide on the other hand was not significantly different in the two groups. These data suggest that T lymphocyte function as measured by mitogenic response to phytohaemagglutinin and concanavalin A is impaired in mice exposed chronically to low concentrations of lead. [ABSTRACT FROM AUTHOR] |
| Databáze: |
Complementary Index |
| Externí odkaz: |
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