Characteristics and evaluation of atherosclerotic plaques: an overview of state-of-the-art techniques.

Autor: Zhiwei He, Jiaying Luo, Mengna Lv, Qingwen Li, Wei Ke, Xuan Niu, Zhaohui Zhang
Předmět:
Zdroj: Frontiers in Neurology; 2023, p1-18, 18p
Abstrakt: Atherosclerosis is an important cause of cerebrovascular and cardiovascular disease (CVD). Lipid infiltration, inflammation, and altered vascular stress are the critical mechanisms that cause atherosclerotic plaque formation. The hallmarks of the progression of atherosclerosis include plaque ulceration, rupture, neovascularization, and intraplaque hemorrhage, all of which are closely associated with the occurrence of CVD. Assessing the severity of atherosclerosis and plaque vulnerability is crucial for the prevention and treatment of CVD. Integrating imaging techniques for evaluating the characteristics of atherosclerotic plaques with computer simulations yields insights into plaque inflammation levels, spatial morphology, and intravascular stress distribution, resulting in a more realistic and accurate estimation of plaque state. Here, we review the characteristics and advancing techniques used to analyze intracranial and extracranial atherosclerotic plaques to provide a comprehensive understanding of atheroma. [ABSTRACT FROM AUTHOR]
Databáze: Complementary Index