Monitoring of oxidative stress and TNF-α status during the healing process in hair goats with metritis.

Autor: Kurt, Serdal, Eşki, Funda, Mis, Leyla
Předmět:
Zdroj: Turkish Journal of Veterinary Research; 2022, Vol. 6 Issue 1, p15-18, 4p
Abstrakt: Objective: This study aimed to monitor oxidative stress parameters including total antioxidant status (TAS) and total oxidant status (TOS), and tumor necrosis factor-alpha (TNF-α) level during the healing process in hair goats with metritis. Materials and Methods: This study was carried out on a total of 25 hair goats with metritis (n=10; Group 1) and healthy (n=15; Group 2). The beginning of the study was accepted as day 0. In both Group 1 and Group 2, blood samples were collected on days 0 (first measurement day), 14 (second measurement day) and 28 (third measurement day) of the study for TAS, TOS and TNF-α analyzes. In addition, oxidative stress index (OSI) was calculated using TAS and TOS values. Results: It was found that TAS level decreased in Group 1 compared to Group 2 at the first measurement day (p<0.05). However, TOS, OSI and TNF-α levels increased in Group 1 compared to Group 2 (p<0.01). At the second measurement day, TOS and OSI values were higher in Group 1 than Group 2 (p<0.05). Conclusion: In conclusion, the antioxidant system weakened, oxidative stress and TNF-α levels increased in animals with metritis compared to healthy animals. However, at the third measurement time, all parameters became similar between groups. [ABSTRACT FROM AUTHOR]
Databáze: Complementary Index