| Autor: |
Urescu, Dumitrita, Musteata, Vasile, Sghibneva-Bobeico, Nina, Robu, Maria, Sporis, Natalia, Pinzari, Stela |
| Předmět: |
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| Zdroj: |
German International Journal of Modern Science / Deutsche Internationale Zeitschrift für Zeitgenössische Wissenschaft; Oct2023, Issue 66, p39-43, 5p |
| Abstrakt: |
What is not yet known on the issue addressed in the submitted Manuscript Despite the development of new methods of diagnosis and treatment with antineoplastic agents, the results of aggressive NHL treatment remain modest, with frequent relapses and primary refractory forms. Research hypothesis It was carried out a qualitative, analytical study, with a narrative synthesis of the literature, as well as studying the group of patients included in the study to detect the challenges that lead to the delay in establishing the diagnosis of aggressive extranodal NHL. The novelty added by manuscript to the already published scientific literature Conducting a broad literature synthesis to demonstrate the importance of continuing research in the field of extranodal aggressive NHL, which remains a current problem of contemporary hemato-oncology and public health. Introduction: Non-Hodgkin's lymphomas form a group of malignant tumors, which develop from extramedullary hematopoietic cells. They are one of the most common forms of hemoblastosis. Diseases can develop in people of any age. The morbidity of NHL increases with age reaching the highest level in people over 50 years of age. The aim of the study was to identify the causes that lead to difficulties in establishing the diagnosis of aggressive extranodal non-Hodgkin's lymphoma. Material and methods: It was carried out a qualitative, analytical study. The article assumed both the research of the specialized literature and the processing of the information within the research group in order to present the most conclusive data related to the current problems in establishing the diagnosis of aggressive extranodal NHL. Results: Aggressive extranodal NHL remains a major problem, with a clear increase in the annual number of cases globally. This trend is observed in several countries of the world, thus morbidity increases by 3% annually in women and by 4% in men. Worldwide, aggressive NHL continues to predominantly affect the working population. Although patients with primary extranodal NHL tend to present to the medical specialist at a lower stage than those with primary nodal disease, the number of those presenting at advanced stages continues to remain high. Conclusions: Although the diagnosis of NHL does not involve great impediments, patients are often detected in the late stages of the disease either because of late referral to a doctor or because of incorrect diagnosis by primary care physicians. Despite the development of new methods of diagnosis and treatment, extranodal aggressive NHL continues to be a current problem of clinical medicine and public health, requiring increased managerial and financial efforts. [ABSTRACT FROM AUTHOR] |
| Databáze: |
Complementary Index |
| Externí odkaz: |
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