| Autor: |
Gür, Volkan, Yapıcı, Furkan, Subaşı, İzzet Özay, Gökgöz, Mehmet Burak, Gülhan, Barış, Çıkman, Aytekin, Karakeçili, Faruk, Koçkara, Nizamettin |
| Předmět: |
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| Zdroj: |
Archives of Basic & Clinical Research; Sep2023, Vol. 5 Issue 3, p350-354, 5p |
| Abstrakt: |
Objective: Staphylococcus aureus is a critical infectious agent in orthopedics and traumatology clinics. Treatment of S. aureus infection is a problem, mainly due to the increased incidence of methicillin-resistant strains. This study aims to determine the antibiotic resistance of S. aureus strains isolated from wound samples of patients admitted to a tertiary care hospital's orthopedics and traumatology clinic. Methods: Patients admitted to our hospital's orthopedics and traumatology clinic between January 2012 and November 2018 were included in this study and studied retrospectively. Participants in the study were required to have S. aureus strains present within their wounds. In addition to more traditional approaches, an automated microbiologic agent detection system known as VITEK® 2 Compact (bioMérieux, Marcy l'Etoile, France) was utilized in this study to identify S. aureus and determine its level of antibiotic resistance. Results: S. aureus was identified in 64 out of 298 wound samples, with a detection rate of 21.5%. Fifty-one S. aureus strains (79.7% of the total) were taken from the inpatient clinic, and the remaining 13 (20.3%) were obtained from the outpatient clinic. S. aureus strains were categorized as either methicillin-resistant S. aureus positive (19 patients, 29.7%) or methi cilli n-sus cepti ble S. aureus positive (45 patients, 70.3%), with the majority being methi cilli n-sus cepti ble S. aureus positive. Conclusion: We found out that among methicillin-resistant S. aureus positive patients, vancomycin, teicoplanin, linezolid, tigecycline, and daptomycin were effective antibiotic agents for the treatment. Also, methicillin-resistant S. aureus positive patients were resistant to penicillin, rifampicin, tetracycline, and erythromycin. This study detected methicillin resistance as a significant issue, and S. aureus strains antibiotic resistance in our study population was comparable to previous research. [ABSTRACT FROM AUTHOR] |
| Databáze: |
Complementary Index |
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