Hypersensitivity to the diphtheria component in the Di-Te-Pol vaccine. A type I allergic reaction demonstrated by basophil histamine release.

Autor: Skov, Per Stahl, Pelck, Inger, Ebbesen, Finn, Poulsen, Lars Kærgaard
Předmět:
Zdroj: Pediatric Allergy & Immunology; Aug1997, Vol. 8 Issue 3, p156-158, 3p, 1 Chart
Abstrakt: We describe a two year-old multiallergic boy who developed generalized urticaria after the third Di-Te-Pol vaccination. A Type I reaction to the vaccine was demonstrated by performing basophil histamine release to the complete vaccine. Further, we found that the reaction could be exclusively ascribed to Diphtheria-Toxoid whereas no release was observed by the Polio and Tetanus component. The latter result was confirmed since no specific IgE to Tetanus Toxoid could be demonstrated. [ABSTRACT FROM AUTHOR]
Databáze: Complementary Index