| Autor: |
Fazio, Gregory, Veltri, Enrico P., Tomaselli, Gordon, Lewis, Richard, Griffith, Lawrence S. C., Guarnieri, Thomas |
| Předmět: |
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| Zdroj: |
Pacing & Clinical Electrophysiology; Nov1991, Vol. 14 Issue 11, p1905-1910, 6p, 1 Diagram, 1 Chart, 1 Graph |
| Abstrakt: |
We analyzed our 10-year cumulative experience of 40 consecutive patients with idiopathic dilated cardiomyopathy and associated ventricular tachyarrhythmias, treated with implantable cardioverter defibrillators. Dilated cardiomyopathy was defined as left ventricular ejection fraction (EF) ≤ 50% with no defineable etiology. Patient characteristics included: 24 male, mean age 52 years, mean EF = 33%, New York Heart Association Class I-III, presenting syndrome--cardiac arrest (n = 28), syncope/near syncope (n = 12). At 2.5 years mean follow-up, there were 16 deaths: one operative, three sudden, two incessant ventricular tachycardia/ventricular fibrillation (VT/VF), six heart failure, and four noncardiac. The actuarial mortality at 1 and 4 years was 0% and 14% for sudden death, 11% and 34% for cardiac death. The projected mortality was 52% and 78% for same time intervals (P < 0.01). No useful baseline variable predicted who would or would not receive an ICD shock in follow-up. ICD therapy appears effective in reducing sudden death mortality in this high risk population. [ABSTRACT FROM AUTHOR] |
| Databáze: |
Complementary Index |
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