| Autor: |
Singer, Igor, Van Der Laken, Jacoba, Edmonds Jr., Harvey L., Slatera, A. David, Austin, Erle, Shields, Christopher B., Kupersmith, Joel |
| Předmět: |
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| Zdroj: |
Pacing & Clinical Electrophysiology; Nov1991, Vol. 14 Issue 11, p1899-1904, 6p, 1 Diagram |
| Abstrakt: |
Determination of defibrillation thresholds (DFTs) and implantable cardioverter defibrillator (ICD) testing requires repeated inductions of ventricular fibrillation (VF) and defibrillation attempts using known energy outputs. Little is known about the individual and cumulative effects of repetitive brief episodes of VF and hypoperfusion an cerebral function. The potential clinical utility of quantitative electroencephalographic (QEEG) monitoring during intraoperative ICD testing, by using processed 19-channel EEG (0.5-35 Hz bandwidth), was examined in ten anesthetized patients, five males and five females (mean age 62 ± 10 years), who underwent ICD implantation and testing. Ischemic QEEG patterns were defined as those with a 3 standard deviation increase (P < 0.01) in absolute delta (1.5-3.5 Hz) power persisting for ≥ 2.5 minutes. The majority (80%) of the VF episodes (70) were accompanied by QEEG "slowing" (doubling of the pre-VF low frequency delta waves amplitude). All the patients (5/5) experiencing > 6 VF episodes showed a statistically significant increase in the low frequency amplitude. In contrast, this EEG abnormality was apparent in only one of five patients experiencing < 6 VF episodes. These results suggest a cumulative QEEG depression associated with ICD testing. QEEG may provide an objective means for establishing an individualized upper safe limit of DFT testing and the total number of induced VF episodes. [ABSTRACT FROM AUTHOR] |
| Databáze: |
Complementary Index |
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