| Autor: |
Alqaisi, Khalid M., Al-Qaisi, Talal S., Alhmoud, Jehad F., Farah, Husni S., Hamdan, Thamer A., Ahmed, Khaled A., Elbadrawy, Elsayed |
| Předmět: |
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| Zdroj: |
Tropical Journal of Natural Product Research; Sep2023, Vol. 7 Issue 9, p4026-4031, 6p |
| Abstrakt: |
Pomegranates are one of the fruits that are most frequently consumed in the Middle East and have a medical effect. This study aimed to examine the antidiabetic and antilipidemic effect of pomegranate fruits parts including peels, seeds, and rinds extracted using ethanol on the blood glucose, cholesterol, triglyceride, low-density lipoprotein (LDL), high-density lipoprotein (HDL), and very-low-density lipoprotein (VLDL). Control (non-treated) rats and alloxandiabetic-induced rats were used in this study. The alloxan-diabetic-induced rats were divided into four groups and each group received a subcutaneously injected either peels, seeds, or grind ethanol extract, and a group was treated with the drug glipizide for 28 days. Data showed a significant effect for the pomegranate peels and rind ethanol extract in lowering glucose levels (P = 0.0295) with no significant effect for the juice extract on blood glucose levels. Cholesterol, triglycerides, LDL, and VLDL were all significantly reduced by the pomegranate fruit component extracts employed in this study (P = 0.014). However, no significant effect was observed for any extract on the HDL levels in the blood (P > 0.5). In conclusion, the rind of the pomegranate can be used in optimizing blood lipid profile and glucose, in addition to seeds and peels. [ABSTRACT FROM AUTHOR] |
| Databáze: |
Complementary Index |
| Externí odkaz: |
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