Cytotoxic Activity of Xanthones from the Stem Bark of Cratoxylum sumatranum.

Autor: Mardhiyyah, Shola, Zakiyah, Mufidatuz, Renata, Erika D., Tjahjandarie, Tjitjik S., Supratman, Unang, Retnowati, Rurini, Saputri, Ratih D., Tanjung, Mulyadi
Předmět:
Zdroj: Tropical Journal of Natural Product Research; Sep2023, Vol. 7 Issue 9, p3908-3910, 3p
Abstrakt: Two xanthones, gerontoxanthone I and macluraxanthone, were isolated from the stem bark of Cratoxylum sumatranum. Their structures were determined based on UV, HRESI-MS, 1D, and 2D NMR spectral data. Compounds 1 and 2 showed high activity against T47D cells with an IC50 of 1.10 and 1.60 μg/mL. [ABSTRACT FROM AUTHOR]
Databáze: Complementary Index