Predictive Factors for the Prognosis of Vogt-Koyanagi-Harada Disease.

Autor: Kaya, Pınar, İnanç Tekin, Merve, Özdal, Pınar Çakar
Předmět:
Zdroj: Ocular Immunology & Inflammation; Oct2023, Vol. 31 Issue 8, p1687-1693, 7p
Abstrakt: To identify the prognostic factors in Vogt–Koyanagi–Harada (VKH) disease. This study included 23 patients (46 eyes) with acute-phase VKHdivided into two subgroups: Group 1; acute-resolved (10 patients), group 2; chronic-recurrent (13 patients). Mean age were 29.5 ± 10.2 years in group 1, 35.8 ± 12.2 years group 2 (p =.033). Best-corrected visual acuity with logMAR at admission was 0.91 ± 0.65 in group 1, 0.88 ± 0.62 in group 2 (p =.798), and improved to 0.08 ± 0.24, 0.18 ± 0.6, respectively (p =.557). Extraocular findings were detected in 30% in group 1, and 53.8% in group 2 at the time of admission (p =.108). All patients were treated with 1 g/day 3–5 days intravenous steroid, and 10 patients had immunomodulatory treatment. Initiation of immunomodulatory therapy did not affect the prognosis (p =.676). Older patients and/or who developed extraocular findings at the presentation were more prone to show recurrences. [ABSTRACT FROM AUTHOR]
Databáze: Complementary Index
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