| Autor: |
Santos, Maryana Cruz, de Gois Andrade, Gabriela Vilanova, da Mota Santana, Lucas Alves, Sabey, Mark Jon Santana, Barbosa, Breno Ferreira, de Albuquerque, Hélio Igor Melo, Floresta, Lara Góis, Gonçalo, Rani Iani Costa, Queiroz, Lélia Maria Guedes, Ayres, Lucas Celestino Guerzet |
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| Zdroj: |
Oral Surgery (1752-2471); Nov2023, Vol. 16 Issue 4, p384-386, 3p |
| Abstrakt: |
Probably, this pathophysiological mechanism may have occurred in our case, once both lesions share cystic morphology as well as epithelial lining of odontogenic nature. Ameloblastoma is a benign epithelial odontogenic tumour, although it shows an aggressive behaviour with high recurrence rates in jaws.[1] Several studies have associated its pathogenesis with mutation in BRAF gene (MAPK/ERK pathway), being this a potential target to the development of inhibitory therapies.[[2]] Traditionally, the main therapeutic modalities to ameloblastoma include surgical resection and conservative approaches to solid and unicystic forms, respectively.[4] However, the risk associated with these interventions, such as aesthetic damage, morbidity and potential of recurrence, has provoked controversy about the best treatment option.[5] Besides, some cases of unicystic ameloblastoma (UA) may require radical intervention, especially mural subtype.[6] In order to clarify this question, we report here a case of an aggressive mural UA treated with a conservative approach and detailed clinical-radiographic and histological follow-up. Intraoral examination revealed a slight bulging in the buccal region of the lower left molars, with an absence of mobility of dental units in contact with the lesion (Figure 1A). [Extracted from the article] |
| Databáze: |
Complementary Index |
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