| Abstrakt: |
Purpose: To investigate the impact of MRI patient‐specific geometrical distortion (PSD) on the quality of Gamma Knife stereotactic radiosurgery (GK‐SRS) plans of the vestibular schwannoma (VS) tumors. Methods and materials: Three open access datasets including the MPI‐Leipzig Mind‐Brain‐Body (318 patients), the slow event‐related fMRI designs dataset (62 patients), and the VS dataset (242 patients) were used. We used first two datasets to train a 3D convolution network to predict the distortion map of third dataset that were then used to calculate and correct the PSD. GK‐SRS plans of VS dataset were used to evaluate dose distribution of PSD‐corrected MRI images. GK‐SRS prescription dose of VS cases was 12 Gy. Geometric and dosimetric discrepancies were assessed between the dose distributions and contours before and after the PSD corrections. Geometry indices were center of the contours, Dice coefficient (DC), Hausdorff distance (HD), and dosimetric indices were Dμ${D_\mu }$, Dmax${D_{max}}$, Dmin${D_{min}}$, and D95%${D_{95{\mathrm{\% }}}}$ doses, target coverage (TC), Paddick's conformity index (PCI), Paddick's gradient index (GI), and homogeneity index (HI). Results: Geometric distortions of about 1.2 mm were observed at the air‐tissue interfaces at the air canal and nasal cavity borders. Average center of the targets was significantly distorted along the frequency encoding direction after the PSD‐correction. Average DC and HD metrics were 0.90 and 2.13 mm. Average Dμ${D_\mu }$, D95%,${D_{95{\mathrm{\% ,}}}}$ and Dmin${D_{min}}$ in Gy significantly increased after PSD correction from 16.85 to 17.25, 12.30 to 12.77, and from 8.98 to 9.92. Dmax${D_{max}}$ did not significantly change after the correction. Average TC and PCI significantly increased from 0.97 to 0.98, and 0.94 to 0.96. Average GI decreased significantly from 2.24 to 2.15 after PSD correction. However, HI did not significantly change after the correction. Conclusion: The proposed method could predict and correct the PSD that indicates the importance of PSD correction before GK‐SRS plans of the VS patients. [ABSTRACT FROM AUTHOR] |
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