| Autor: |
An, Nguyen Thi Kim, Van Hien, Nguyen, Thi Thuy, Nguyen, Lan Phuong, Doan, Gia Bach, Ha, Tra, Nguyen Thanh, Quang Tung, Nguyen, Tham, Pham Thi, Tai, Bui Huu, Thu Thuy, Tran Thi |
| Předmět: |
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| Zdroj: |
Natural Product Research; 2023, Vol. 37 Issue 21, p3668-3676, 9p |
| Abstrakt: |
Three new xanthones, garcicowanones C-E (1 − 3), and six known xanthones (4 − 9) were isolated from the roots of Garcinia cowa Roxb. ex Choisy. Their chemical structures were determined using spectroscopic technics, including HR-ESI-MS and 2 D NMR. All isolated compounds were evaluated for in vitro α-glucosidase inhibition. Cowanol (6) and norcowanin (8) had the most potent α-glucosidase inhibitory activity, with respective IC50 values of 33.5 ± 0.8 and 17.2 ± 0.3 µM, compared with the positive control, acarbose (IC50 257.3 ± 4.8 µM). [ABSTRACT FROM AUTHOR] |
| Databáze: |
Complementary Index |
| Externí odkaz: |
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