| Autor: |
Qin, Haijuan, Zhou, Ningning, Wang, Kun, Zhang, Ying, Zhao, Xia, Lu, Kui |
| Předmět: |
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| Zdroj: |
Synlett; 10/24/2023, Vol. 34 Issue 17, p2037-2041, 5p |
| Abstrakt: |
[45][46][47] Herein, we report a visible-light-induced C(3) difluoroalkylation of quinoxalin-2(1 I H i )-ones B 1 b with these difluoroiodane(III) reagents under catalyst-free conditions (Scheme 1, equation 7). The readily accessible reagents and the mild reaction conditions make this reaction an alternative and practical strategy for the synthesis of C3-difluoroalkylated quinoxalin-2(1 I H i )-ones. Keywords: difluoroalkylation; quinoxalinones; hypervalent iodine reagents; photocatalysis; catalyst-free reaction EN difluoroalkylation quinoxalinones hypervalent iodine reagents photocatalysis catalyst-free reaction 2037 2041 5 10/09/23 20231024 NES 231024 Graph Quinoxalin-2(1 I H i )-ones have been recognized as a privileged class of structural motifs existing in various bioactive natural products and pharmaceutical compounds. Difluoroalkylation, quinoxalinones, hypervalent iodine reagents, photocatalysis, catalyst-free reaction. [Extracted from the article] |
| Databáze: |
Complementary Index |
| Externí odkaz: |
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