| Autor: |
Saad Shaukat, Muhammad Hamza, Fiegen, Noah, Malik, Muhammad Nauman, Petrasko, Marian |
| Zdroj: |
BMJ Case Reports; Sep2023, Vol. 16 Issue 9, p1-2, 2p |
| Abstrakt: |
A nulligravid woman in her mid-20s with colchicineintolerant, steroid-dependent recurrent idiopathic pericarditis was in remission for 2years on anakinra monotherapy when she had an unplanned pregnancy. Due to very limited and conflicting data, European Alliance of Associations for Rheumatology and American College of Rheumatology guidelines are equivocal on the use of anakinra in pregnancy, emphasising an individualised approach. Anakinra was discontinued but a month later, in the second month of gestation, the patient had an acute pericarditis flare. A multidisciplinary, patient-centred discussion about the competing risks of infection, obstetric complications and fetal malformations with anakinra versus suboptimally managed recurrent acute pericarditis guided the patient to choosing improved symptom control. Chest pain resolved and CRP normalised after daily anakinra injections were resumed. In the second trimester, the patient had mild COVID-19 infection and streptococcal pharyngitis on anakinra. At 34 weeks gestation, the patient went into preterm labour and had a spontaneous vaginal delivery of a healthy neonate. [ABSTRACT FROM AUTHOR] |
| Databáze: |
Complementary Index |
| Externí odkaz: |
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