| Autor: |
Liu, Wen-jing, Li, Hai-Juan, Zou, Xiaoran, Liu, Qian, Ma, Fei, Zhang, Chun-yang |
| Předmět: |
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| Zdroj: |
Chemical Communications; 10/11/2023, Vol. 59 Issue 79, p11807-11810, 4p |
| Abstrakt: |
We construct a sensitive chemiluminescent biosensor for sensitive detection of cytosine deaminase APOBEC3A based on deamination-triggered exponential signal amplification. This biosensor displays good specificity and high sensitivity, and it can screen APOBEC3A inhibitors and measure endogenous APOBEC3A at the single-cell level, with prospective applications in disease diagnostics and therapy. [ABSTRACT FROM AUTHOR] |
| Databáze: |
Complementary Index |
| Externí odkaz: |
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