The Different Types of Metallophores Produced by Salmonella enterica : A Review.

Autor:	Mohsen, Yehya, Tarchichi, Nathalie, Barakat, Rana, Kawtharani, Inas, Ghandour, Rayane, Ezzeddine, Zeinab, Ghssein, Ghassan
Předmět:	GENETIC regulation HEAVY metals SALMONELLA enterica serovar Typhi GRAM-negative bacteria SALMONELLA enterica METABOLITES GASTROENTERITIS
Zdroj:	Microbiology Research; Sep2023, Vol. 14 Issue 3, p1457-1469, 13p
Abstrakt:	Salmonella enterica (S. enterica) serovars Enteritidis and Typhimurium are the main causes of bacterial gastroenteritis worldwide. This Gram-negative rods bacterium possesses several virulence factors that enable it to survive the host's nutritional immunity. Toxins and metallophores are among these factors. Heavy metals, in particular, are essential for the survival of all living organisms including bacteria. During infection, S. enterica competes with the host for the available heavy metals by secreting metallophores, which are secondary metabolites. Once produced in the extracellular medium, metallophores complex heavy metals thus allowing Salmonella to acquire metal ions through importing them via channels embedded in their membranes. This review highlights the biosynthesis, export, import, and genetic regulation of different metallophores synthesized by this germ. [ABSTRACT FROM AUTHOR]
Databáze:	Complementary Index
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