Liver metastases of colorectal adenocarcinoma with intrahepatic biliary spread pattern: clinical manifestation and importance of immunohistochemical analysis.

Autor: Díaz Vico, Tamara, Castellón Pavón, Camilo José, Díaz García, Gustavo Adolfo, Torres Alemán, Ana, Pérez Domene, María Teresa, Sánchez Infante, Silvia, Fuel Gómez, Daniela Carolina, Durán Poveda, Manuel
Zdroj: Clinical Journal of Gastroenterology; Oct2023, Vol. 16 Issue 5, p693-697, 5p
Abstrakt: Liver metastases of colorectal carcinoma (LMCC) with macroscopic intrabiliary ductal involvement are a rare entity that can clinically and radiologically mimic a cholangiocarcinoma. However, a thorough anatomopathologic and immunohistochemical study of biliary ductal involvement is required because of its distinctive clinical features and relatively indolent biological behavior, reflecting a better prognosis and long-term survival. We present the case of a patient who debuted with LMCC with intrahepatic biliary ductal involvement, whose definitive diagnosis was established by immunohistochemical analysis, showing a characteristic CK7 − /CK20 + pattern. [ABSTRACT FROM AUTHOR]
Databáze: Complementary Index