A pilot study on the use of a perfluorohexyloctane/silicone oil solution as a heavier than water internal tamponade agent.

Autor: D. Wong, Van Meurs, J. C., Stappler, T., Groenewald, C., Pearce, I. A., McGalliard, J. N., Manousakis, E., Herbert, E. N.
Předmět:
Zdroj: British Journal of Ophthalmology; Jun2005, Vol. 89 Issue 6, p662-665, 4p, 3 Charts
Abstrakt: Aims: To report a prospective two centred non-comparative interventional pilot study of a solution of perfluorohexyl-octane and silicone oil (Densiron-68) as a heavier than water internal tamponade. Methods: 42 consecutive patients were recruited. The indications include proliferative vitreoretinopathy, retinal detachments arising from inferior retinal breaks, and inability to posture. Results: The success rate with one operation using Densiron was 81% and with further surgery 93%. At the end of the study all tamponade agents were removed in 90% of patients. Visual acuity improved from mean logMAR of 1.41 (SD 0.64) to 0.94 (SD 0.57), p = 0.001. There was little evidence of dispersion and excessive inflammation. Conclusion: This new tamponade agent is being compared to conventional silicone oil in a prospective international randomised trial. [ABSTRACT FROM AUTHOR]
Databáze: Complementary Index