A Non-Electrolysis Bioelectric Effect for Gingivitis and Hygiene Contamination Biofilm Removal.

Autor: Kim, Young Wook, Lee, Jihyun, Han, Sang Kuy, Koo, Bon-Sang, Park, Taeguen, Park, Hyun Mok, Lee, Byoungdoo
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Zdroj: Applied Microbiology (2673-8007); Sep2023, Vol. 3 Issue 3, p675-686, 12p
Abstrakt: A combinatorial biofilm treatment involving a low dose of antibiotics along with a small amount of electricity is known as the bioelectric effect (BE). When an external electric field or current is applied, biofilms can be affected by the resulting electrostatic force. Our group is researching the maximization of electrostatic force through the integration of both alternating and direct currents, with a voltage below the electrolysis threshold (0.82 V). To validate the efficacy of this technology, in the present work we investigated two major biofilm applications: (1) dentistry for oral biofilm infection and (2) hygiene for aerobic biofilm contamination. For each application, testing devices were developed in the form of a toothbrush and an evaporator cleaner, respectively. The dental clinical results demonstrated a 75% reduction in gingivitis compared to the non-BE applied group (n = 40, ANOVA, paired t-test, p < 0.05). Meanwhile, the hygiene testing result demonstrated an 81.8% increase in biofilm removal compared to the initial untreated sample (n = 6, ANOVA, paired t-test, p < 0.05). In conclusion, this new BE technology showed efficacy in both dental- and hygiene-associated biofilms without causing electrolysis. Further investigation and development of the BE system should continue in both the medical and hygiene fields. [ABSTRACT FROM AUTHOR]
Databáze: Complementary Index
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