| Autor: |
Ghanta, Jyotirmoy, Panja, Buddhadev, Bhushan, Bibhuti, Maji, Kausik, Kundu, Somenath, Sen, Sukanta |
| Předmět: |
|
| Zdroj: |
Indian Journal of Public Health Research & Development; Jul-Sep2023, Vol. 14 Issue 3, p111-117, 7p |
| Abstrakt: |
Introduction: Increased occurrence of tuberculosis in diabetic population is known since long time. Tuberculosis (TB) remains one of the world’s deadliest communicable diseases and India currently bears the highest burden of tuberculosis in the World. Diabetes mellitus (DM) is becoming the epidemic of the 21st century with India having the second largest diabetic populationglobally. This emphasizes the importance of investigating the association of tuberculosis and diabetes mellitus. Aim: To evaluate clinic-radiological presentations of tuberculosis (pulmonary and extra pulmonary) in diabetic patients compared to non-diabetic patients. Materials and Methods: Patients with active tuberculosis with and without diabetes mellitus were enrolled and the two groups were matched for age, sex, addiction habits, history of contact with tuberculosis and previous treatment for tuberculosis. Spectrums of tubercular involvement in both the groups were studied including severity of the disease. A symptom score comprising major TB related symptoms and a composite severity score utilizing clinical, radiological, and microbiological parameters were used to compare TB severity between the two groups. Results: Patients with TB with DM were found to have male preponderance (70%), higher BMI, increased chance of having isolated lower lobe lesion (8%), multilobar lesion (42%) and cavitary lesion (20%), significantly higher TB symptom score and TB severity score compared to patients with TB without DM. The TB severity score has significant correlation with level of HbA1c at presentation. Conclusion: Presence of coexistent diabetes along with tuberculosis results in increased severity of tuberculosis and its severity has direct correlation with poor glycemic status at presentation. [ABSTRACT FROM AUTHOR] |
| Databáze: |
Complementary Index |
| Externí odkaz: |
|
