| Autor: |
Giannis, Dimitrios, Geropoulos, Georgios, Kakos, Christos D, Lu, Weiying, El Hadwe, Salim, Fornasiero, Massimiliano, Robertson, Andrew, Parmar, Chetan |
| Předmět: |
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| Zdroj: |
Obesity Surgery; Oct2023, Vol. 33 Issue 10, p2991-3007, 17p |
| Abstrakt: |
Introduction : Portomesenteric vein thrombosis (PMVT) is a rare but potentially fatal complication of sleeve gastrectomy (SG). The rising prevalence of SG has led to a surge in the occurrence of PMVT, while the associated risk factors have not been fully elucidated. This study aims to determine the incidence and risk factors of PMVT in patients undergoing SG. Methods : A comprehensive literature search was performed in PubMed and EMBASE databases. Proportion and regression meta-analyses were conducted. Results : In a total of 76 studies including 101,914 patients undergoing SG, we identified 357 patients with PMVT. Mean follow-up was 14.4 (SD: 16.3) months. The incidence of PMVT was found to be 0.50% (95%CI: 0.40–0.61%). The majority of the population presented with abdominal pain (91.8%) at an average of 22.4 days postoperatively and PMVT was mainly diagnosed with computed tomography (CT) (96.0%). Hematologic abnormalities predisposing to thrombophilia were identified in 34.9% of the population. Advanced age (p=0.02) and low center volume (p <0.0001) were significantly associated with PMVT, while gender, BMI, hematologic abnormality, prior history of deep vein thrombosis or pulmonary embolism, type of prophylactic anticoagulation, and duration of prophylactic anticoagulation were not associated with the incidence of PMVT in meta-regression analyses. Treatment included therapeutic anticoagulation in 93.4% and the mortality rate was 4/357 (1.1%). Conclusion : PMVT is a rare complication of sleeve gastrectomy with an incidence rate <1% that is associated with low center volume and advanced age but is not affected by the duration or type of thromboprophylaxis administered postoperatively. [ABSTRACT FROM AUTHOR] |
| Databáze: |
Complementary Index |
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